Osteosarcoma: features Mnemonic

PEARL HARBOR:

Paget's disease (10-20%)*
Early age (10-20 yrs)
Around knee
Raised periosteum by expanding tumor: "sunburst pattern"
Lace-like architecture

Hyaline arteoriosclerosis
Alkaline phosphatase increased
Retinoblastoma*
Boys, predominantly
Osteomyelitis DDx
Radiation*

Sunburst pattern was Japanese Navy emblem during WWII.
*: Predisposing factors.