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Tuesday, February 3, 2015

Hemolytic Anemia Causes / Differential Diagnosis Mnemonic

HEMATOLOGIST

Hemoglobinopathy: Hb SS, SC, S beta Thal
            Hemoglobinuria: Paroxysmal Nocturnal Hemoglobinuria.
Enzyme Deficiency- Inherited Pyruvate Kinase (PK) deficiency 
.           and pyrimidine-5'-nucleotidase deficiency
Medication - Drug induced immune hemolytic anemias
Antibodies, autoimmune
Trauma to the red cells. Fragmentation (Microangiopathic)
Ovalocytosis - This is an autosomal dominant disorder seen in                      people from South East Asia. Signs and symptoms are                      minimal.
Liver disease .
Osmotic fragility in Hereditary spherocytosis and in Hereditary                    Eliptocytosis
Glucose - 6 - Phosphate Dehydrogenase Deficiency (G6PD)
Infection: Intra-erythrocytic parasites (malaria and babesiosis)
Splenic destruction in hyperslenism. Splenomegaly,
Transfusion related Thalassemias - 

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